Study on fingerprint spectra of different medicinal parts of Poria cocos
10.3760/cma.j.cn115398-20250121-00252
- VernacularTitle:茯苓不同药用部位指纹图谱研究
- Author:
Yifei MA
1
;
Lin ZHOU
;
Xiangyuan ZHOU
;
Yong LIU
;
Qiong LUO
;
Minyou HE
;
Zhenyu LI
;
Roushan CHEN
;
Wenhui LUO
;
Dongmei SUN
;
Xiangdong CHEN
Author Information
1. 广东一方制药有限公司 广东省中药配方颗粒企业重点实验室，佛山 528244
- Keywords:
Poria (TCD);
Medicinal portions;
Quality control;
Principal component analysis
- From:
International Journal of Traditional Chinese Medicine
2025;47(11):1586-1594
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish a method for the determination of triterpenes and nucleosides in Poria based on HPLC; To accurately determine the various bioactive components in Poria.Methods:Similarity evaluation, clustering analysis and principal component analysis were used to analyze the similarities and differences of different medicinal parts of Poria, and the key chromatographic peaks that could reflect the characteristics were found.Results:The Poricoic acid A and dehydroeburiconic acid could be used as the identification basis for Poriae Cutis and White Poria; at the same time, Polyporenic acid C, dehydropachymic acid and dehydrotrametenolic acid could be used to evaluate Rubra Poria and Poriae Cutis; uridine, guanosine and adenosine may be essential ingredients for evaluating the quality of White Poria, Poriae Cutis and Rubra Poria. In different medicinal parts of Poria, the triterpenes were showed significant differences; by contrary, there were little differences among the same medicinal parts.Conclusion:This study reveals the quality differences between different medicinal parts of Poria, which can provide a scientific basis for the rational application and pharmacodynamic standardization of Poria.
