Exploration on the effects of transcutaneous electrical acupoint stimulation combined with resistance training on stroke related sarcopenia based on propensity score matching method
10.3760/cma.j.cn115398-20241224-00265
- VernacularTitle:基于倾向性评分匹配法探讨经皮穴位电刺激联合抗阻训练对卒中相关性肌少症的影响
- Author:
Xiaoyu LIANG
1
;
Ting ZHU
;
Haiping JIANG
Author Information
1. 上海中医药大学附属曙光医院老年医学科，上海 200021
- Keywords:
Stroke;
Sarcopenia;
Electric stimulation therapy (TCM);
Resistance training;
Integrated Chinese traditional and western medicine therapy
- From:
International Journal of Traditional Chinese Medicine
2025;47(11):1521-1526
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effects of transcutaneous electrical acupoint stimulation (TEAS) combined with resistance training on stroke related muscle atrophy(SRS) based on propensity score matching (PSM) method.Methods:A retrospective analysis was conducted on the clinical data of 150 cases of SRS patients in our hospital from September 2022 to September 2024. The patients were divided into an observation group of 78 cases and a control group of 72 cases according to the treatment method. Using PSM method to balance the confounding factors before treatment in a 1:1 ratio, 40 cases were successfully matched in each group. The control group received resistance training, while the observation group received TEAS treatment in addition to the control group. Both groups received continuous treatment for 12 weeks. Before and after treatment, the MedTrack Length isokinetic muscle strength testing system was used to measure the patients' knee extension and flexion axis muscle strength values, and the body composition analyzer was used to measure the patients' muscle weight and muscle index. The Berg Balance Scale (BBS), Fugl Meyer Motor Function Scale (FMA), and Simplified Upper Limb Function Scale (STEF) were used to evaluate limb motor function. ELISA method was used to detect the levels of muscle growth inhibitor (MSTN), growth differentiation factor 15 (GDF-15), and insulin-like growth factor-1 (IGF-1). The occurrence of adverse reactions during the treatment of two groups and the clinical efficacy was evaluated.Results:The total effective rate of the observation group was 92.50% (37/40), while that of the control group was 75.00% (30/40), with statistical significance ( χ2=4.50, P=0.034). After treatment, the observation group showed higher levels of knee extension [(78.25 ± 6.11) Nm vs. (74.02 ±6.02) Nm, t=3.11], flexion axis muscle strength [(32.84 ± 4.11) Nm vs. (29.35 ± 3.94) Nm, t=3.88], muscle weight [(41.42 ± 3.06) kg vs. (38.29 ± 3.12) kg, t=4.53], and muscle index [(7.11±1.17) kg/m 2vs. (6.56 ± 1.05) kg/m 2, t=2.21] compared to the control group ( P<0.01 or P<0.05). After treatment, the BBS, FMA and STEF scores in the observation group were higher than those in the control group ( t=4.57, 3.23,2.73, respectively, P<0.01), and the levels of serum MSTN [(46.34 ± 5.98) μg/L vs. (51.44 ± 6.04) μg/L, t=3.79] and GDF-15 [(67.44±7.21) μg/L vs. (72.28 ± 8.04) μg/L, t=2.83] in the observation group were lower than those in the control group after treatment ( P<0.01); the level of IGF-1 [(37.92 ±5.66) ng/L vs. (31.09 ± 4.22) ng/L, t=6.11] was higher than that of the control group ( P<0.01). During the treatment period, the incidence of adverse reactions in the observation group was 10.00% (4/40), while in the control group it was 7.50% (3/40), without statistical significance ( χ2=0.16, P=0.692). Conclusion:TEAS combined with resistance training can improve muscle strength and weight in SRS patients, improve limb motor function, reduce serum markers related to muscle attenuation, and have good treatment safety.
