Research progress in the experiments about treatment for kidney diseases with Diaphragma Juglandis Fructus extract
10.3760/cma.j.cn115398-20240921-00050
- VernacularTitle:分心木提取物治疗肾脏疾病实验研究进展
- Author:
Junshao ZHANG
1
;
Mingzhi XIAO
;
Xinxin PANG
;
Di NIU
;
Ruifang CHEN
Author Information
1. 河南中医药大学2022级硕士研究生，郑州 450002
- Keywords:
Kidney diseases;
Diaphragma Juglandis Fructus;
Extract;
Review
- From:
International Journal of Traditional Chinese Medicine
2025;47(10):1489-1492,F4
- CountryChina
- Language:Chinese
-
Abstract:
In the study of kidney ischemia-reperfusion injury, rhabdomyolysis induced kidney injury, hyperuricemia induced kidney injury and other diseases, Diaphragma Juglandis Fructus extract has shown various pharmacological effects such as lowering uric acid, anti-inflammatory, anti-tumor, sedative and sedative effects. It can improve kidney function by reducing inflammatory response, inhibiting oxidative stress, regulating related enzyme activity and other mechanisms. At the same time, Diaphragma Juglandis Fructus extract also has hypoglycemic and lipid-lowering effects, which can regulate glucose and lipid metabolism, inhibit inflammatory reaction, and reduce oxidative stress. It has potential application prospects in the treatment of diabetes nephropathy. At present, current research is mostly focused on animal and cellular experiment levels. Although certain achievements have been made, further clinical research is still needed to clarify its effectiveness and safety in the human body, and to further explore the active components to promote its application in the treatment of kidney diseases in clinical practice.
