Discussion on the medication law of TCM external therapy for the treatment of diabetes foot based on data mining
10.3760/cma.j.cn115398-20250222-00294
- VernacularTitle:基于数据挖掘探讨中药外治法治疗糖尿病足用药规律
- Author:
Wenhan LI
1
;
Hao LI
;
Quanxin LIU
;
Juqin PENG
;
Tianren YU
;
Qiang JIAO
;
Ping WANG
;
Lin SUN
;
Weiwei JIAO
;
Jinbao WANG
Author Information
1. 中国中医科学院望京医院2023级硕士研究生，北京 100102
- Keywords:
Diabetes foot;
Traditional Chinese Medicine;
External therapy;
Medication rule;
Data mining
- From:
International Journal of Traditional Chinese Medicine
2025;47(10):1448-1453
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the medication law of TCM external therapy for the treatment of diabetic foot using data mining methods.Methods:Literature on TCM external treatment for diabetic foot was retrieved from CNKI, Wanfang Data, and Chongqing VIP from the establishment of the databases to June 30, 2024. Excel 2019 software was used to conduct frequency statistics on drug frequency, properties, tastes and meridian tropism, drug efficacy, and commonly used drug pairs. Ancient and Modern Medical Cases Cloud Platform V3.5 was used for association rules, and SPSS Statistics 27.0 was used for complex network analyses.Results:A total of 425 articles were included, involving 328 prescriptions and 232 drugs. The drugs with higher frequency were Carthami Flos, Angelicae Sinensis Radix, Cinnamomi Ramulus, Olibanum, etc. The main tastes were pungent, bitter, and sweet; the main properties were cold and warm; the main meridians were heart, spleen, and liver meridians. The main efficacy was promoting blood circulation and removing blood stasis, clearing heat, and tonifying deficiency; association rule analysis obtained 20 commonly used drug pairs; clustering analysis resulted in four core drug combinations; complex network analysis led to one core prescription.Conclusions:TCM external therapy for diabetic foot follows the guiding principles of "promoting blood circulation and unblocking collaterals, tonifying deficiency and clearing heat" with coordinated regulation of the "heart-liver-spleen meridians". The core prescription and stage-specific formulation strategies reflect a trinity diagnostic and therapeutic approach of "disease differentiation-syndrome differentiation-stage differentiation", providing valuable reference and insights for clinical prescription practices.
