Research progress in clinical and mechanism of Chinese materia medica in the treatment of gastroesophageal reflux disease
10.3760/cma.j.cn115398-20250313-00213
- VernacularTitle:中药治疗胃食管反流病临床及机制研究进展
- Author:
Shuo ZENG
1
;
Suqin HU
;
Yang HU
;
Lei LUO
;
Mingyan LI
;
Qinsheng ZHANG
Author Information
1. 河南中医药大学2023级硕士研究生，郑州 450046
- Keywords:
Gastroesophageal reflux;
Traditional Chinese Medicine;
Mechanism;
Review
- From:
International Journal of Traditional Chinese Medicine
2025;47(10):1479-1483
- CountryChina
- Language:Chinese
-
Abstract:
According to TCM, the main pathogenesis of gastroesophageal reflux disease (GERD) is stomach disharmony and descending, and stomach qi ascending. Phlegm dampness and blood stasis are also important pathological factors of this disease. TCM treatment for GERD mainly starts from the liver, spleen and stomach. The basic treatment is to harmonize the stomach and lower the adverse, and to soothe the liver and relieve depression, invigorate the spleen and resolve dampness, promote qi and blood circulation, and clear heat and inhibit acid. Clinical treatment of GERD is mostly in the form of TCM compounds, often combined with Western medicine, which can improve symptoms, reduce recurrence rate and reduce adverse reactions. The mechanism is to inhibit gastric acid secretion, enhance lower esophageal sphincter pressure, promote gastrointestinal motility, inhibit inflammation, regulate esophageal visceral sensitivity and regulate intestinal flora.
