Exploration on the etiology, pathogenesis and treatment of hepatocellular carcinoma based on the theory of yin excess
10.3760/cma.j.cn115398-20241216-00165
- VernacularTitle:基于阴实理论探讨肝癌的病因病机与治法
- Author:
Yanling JIN
1
;
Si WANG
;
Lei LI
;
You LYU
;
Ciming PAN
;
Jiabao LIAO
Author Information
1. 云南中医药大学基础医学院2022级硕士研究生，昆明 650500
- Keywords:
Liver neoplasms;
Yin excess;
Cold;
Phlegm;
Blood stasis
- From:
International Journal of Traditional Chinese Medicine
2025;47(9):1189-1194
- CountryChina
- Language:Chinese
-
Abstract:
The term yin excess originated in the Huang Di Nei Jing, which refers to the phenomenon of "heavy yin" when wind pathogens invades the human body and defensive qi enters the yin part of the human body. Later doctors have played a role in yin excess. Theoretically, yin and yang are out of balance in the human body, and yin is too much and yang is not enough, which is the process of physiological transformation to pathology; from the diagnosis point of view, patients with yin deficiency have less pulse and more blood; from the clinical manifestations, patients with yin excess appear cold from the back, hands and feet cold reverse; from the point of view of treatment, bitter cold products can cause yin excess. Modern research specifies yin as phlegm, dampness, stasis and other pathological products, and emphasize the relation between yin excess and yang deficiency. Yin excess includes pathological factors such as phlegm stasis cold, external cold straight in the liver wood, set in the hypochasm, resulting in mass; or overthinking and cold drink injury spleen, phlegm turbidiousness, long and hard phlegm forming lumps, thus resulting yin excess; or it may deplete the yang energy of the heart, leading to neglect of the warming function and stagnation of blood stasis; or if the kidney yang is deficient and the body lacks warmth, and there is no true yang in the ridge, then the wood will sink and congest blood stasis; the above etiology and pathogenesis lead to the occupation of yin pathogens, resulting in liver cancer. The treatment methods include liver cold turbidizing, warming liver and dispelling cold, with Wuzhuyu Decoction; spleen-deficiency phlegm production, the treatment should be warm the middle and resolving the phlegm, with Linggui Zhugan Decoction and Zhenwu Decoction; Yang deficiency and stasis, the treatment should warm kidney to remove blood stasis, with Poyu Decoction.
