Research progress in Chaihu Longgu Muli Decoction for the treatment of perimenopausal insomnia
10.3760/cma.j.cn115398-20240913-00162
- VernacularTitle:柴胡加龙骨牡蛎汤治疗围绝经期失眠研究进展
- Author:
Ying LIU
1
;
Jinying FU
;
Yaxin LI
;
Xinyu WANG
;
Xinkun LI
;
Xiang LI
Author Information
1. 河南中医药大学第二临床医学院2022级硕士研究生，郑州 450046
- Keywords:
Chai Hu Long Gu Mu Li Tang;
Perimenopausal insomnia;
Mechanism of action;
Clinical research;
Research progress;
Review
- From:
International Journal of Traditional Chinese Medicine
2025;47(8):1172-1177
- CountryChina
- Language:Chinese
-
Abstract:
Chaihu Longgu Muli Decoction can be used to treat perimenopausal insomnia (PMI). It can be used either alone with modification or in combination with Western medicine or acupuncture and moxibustion and other external TCM treatment methods, which has achieved good efficacy, and can improve the symptoms of patients with difficulty falling asleep and decreased sleep quality, with good safety. The treatment of Chaihu Longgu Muli Decoction for PMI may exert its effects through multiple pathways, such as inhibiting HPA axis hyperactivity, regulating hormone and neurotransmitter levels, inhibiting oxidative stress and inflammatory responses. However, existing clinical studies suffer from issues such as small sample sizes, inconsistent research protocols, and inconsistent efficacy evaluation criteria, which require further improvement and deeper exploration of relevant mechanisms.
