Analysis on current status of clinical trial registration on TCM prevention and treatment of Hashimoto's thyroiditis
10.3760/cma.j.cn115398-20250104-00050
- VernacularTitle:中医药防治桥本甲状腺炎临床研究注册方案分析
- Author:
Weiwei WANG
1
;
Haoyuan JIANG
;
Chen CHEN
;
Dan BI
;
Qin XIE
Author Information
1. 安徽中医药大学2022级硕士研究生，合肥 230012
- Keywords:
Hashimoto disease;
Thyroiditis;
Traditional Chinese Medicine therapy;
Clinical trial registration;
Clinical research
- From:
International Journal of Traditional Chinese Medicine
2025;47(8):1147-1152
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the research programs of clinical trials related to the TCM treatment of Hashimoto's thyroiditis (HT) at home and abroad; To provide references for the follow-up study of TCM treatment of HT.Methods:All clinical research registration plans for TCM prevention and treatment of HT were retrieved from the Chinese Clinical Trial Registry, the International Traditional Medicine Clinical Trial Registry, and the WHO International Clinical Trial Registration Platform from the establishment of the databases to December 31, 2024. Excel 2019 and GraphPad Prism 9.0 were used for data processing, and the basic characteristics, study types, randomized methods, interventions, outcome indicators and other registration information of registered trials with the frequency analysis.Results:A total of 31 clinical trials were included in this study, and the number of registered studies has gradually increased since 2018, which involving 23 clinical institutions in 9 provincial-level administrative regions until 2024. The region with the highest number of registrations is Shanghai (14 items). The funding sources were mainly local financial support and hospital funding. The research types were mostly intervention studies (30 items). The main research design type was randomized parallel controlled trials (27 items).Conclusions:At present, the overall number of registration studies on TCM prevention and treatment of HT is relatively small. However, in recent years, researchers have paid more attention to the registration of clinical trials in this field. The regional distribution of existing trial registration is not balanced, and the research design scheme needs to be improved.
