Exploration on the pathogenesis and TCM diagnosis and treatment of coronary heart disease complicated with anxiety and depression based on the theory of "heart-gallbladder connection"
10.3760/cma.j.cn115398-20240822-00206
- VernacularTitle:基于“心胆相通”理论探析冠心病合并焦虑抑郁发病机制及中医诊疗
- Author:
Guanming HUANG
1
;
Jingjing WANG
;
Yang CHU
;
Feng WU
;
Haoqi LIU
;
Haiming CUI
Author Information
1. 上海中医药大学附属岳阳中西医结合医院心内科，上海 200437
- Keywords:
Coronary disease;
Heart diseases;
Heart gallbladder connection;
Pathogenesis;
Anxiety and depression
- From:
International Journal of Traditional Chinese Medicine
2025;47(7):897-902
- CountryChina
- Language:Chinese
-
Abstract:
As a typical "double heart" disease, the incidence rate of coronary heart disease with anxiety and depression is increasing year by year, which affects the long-term prognosis of the disease and the quality of life of patients. Based on the holistic concept of TCM, the theory of "heart-gallbladder connection" holds that there is a physiological and pathological relationship between the heart and gallbladder. At the same time, the theory of "heart-gallbladder connection" combined with modern medicine points out that disturbances in bile acid metabolism, gallbladder heart reflex, and brain gut bile acid axis are the three key nodes in the development of anxiety and depression in coronary heart disease. Starting from the theory of "heart-gallbladder connection", coronary heart disease combined with anxiety and depression is divided into three syndromes: heart deficiency and timidity, heart gallbladder stagnation, and heart gallbladder fire hyperactivity. Taking the principle of heart gallbladder harmony, the treatment of nourishing the heart and warming the gallbladder, regulating the heart and clearing the gallbladder, and clearing the heart and promoting bile flow is applied to provide a new clinical diagnosis and treatment approach for coronary heart disease combined with anxiety and depression.
