Exploration on medication law of national TCM master Lu Fang in treating primary trigeminal neuralgia based on data mining
10.3760/cma.j.cn115398-20240512-00100
- VernacularTitle:基于数据挖掘探析国医大师卢芳治疗原发性三叉神经痛的用药规律
- Author:
Qi SUN
1
;
Wenyu LAN
;
Rui MA
;
Xiaorui WANG
;
Yuanduo XIA
;
Tianjiao LU
;
Meixi LU
Author Information
1. 哈尔滨市中医医院国医大师工作室，哈尔滨 150076
- Keywords:
Trigeminal neuralgia;
Lu Fang;
Data mining;
R language;
Medication law
- From:
International Journal of Traditional Chinese Medicine
2025;47(4):529-534
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the medication law of national TCM master Lu Fang in the treatment of primary trigeminal neuralgia (PTN) based on data mining.Methods:With the prescription of the outpatient patients of Harbin Traditional Chinese Medicine Hospital of Professor Lu Fang from September 2014 to September 2022 as the data source, the frequency, property and taste, and meridian tropism of the prescribed drugs were analyzed using Excel 2022 software. R 4.2.1 was used for mining analysis on Chinese materia medica, including correlation, relevance, and clustering,and the medication law in the treatment of PTN was discussed.Results:A total of 300 prescriptions were analyzed, involving 177 kinds of Chinese materia medica, with a frequency of 3 120 times, and 34 kinds of of high-frequency Chinese materia medica. The high frequently Chinese materia medica included Chuanxiong Rhizoma, Angelicae Dahuricae Radix, Puerariae Lobatae Radix, Ligustici Rhizoma et Radix, and Viticis Fructus. The main properties were warm, slightly cold, and neutral, while the main tastes were pungent, bitter, and sweet. The meridian tropism analysis ranked the liver, lung, spleen, and stomach meridians in descending order. Analysis yielded 21 strong association rules, and the association analysis formed a core prescription group based on Chuanxiong Rhizoma, Angelicae Dahuricae Radix, and Ligustici Rhizoma et Radix. The analysis obtained 5 types of clustering combinations.Conclusion:Professor Lu Fang's the medication law to treat primary trigeminal neuralgia is mainly dispelling wind and alleviating pain, which is often combined with the methods, such as searching and dredging collaterals, clearing and dispelling the stagnated heat, calming the liver and subduing yang, soothing the liver and invigorating the spleen.
