Exploration on the relationship between exosomes and overlap of symptoms of functional gastrointestinal disorders based on the theory of "holism of five organs"
10.3760/cma.j.cn115398-20240611-00085
- VernacularTitle:基于“五脏一体观”探讨外泌体与功能性胃肠病症状重叠的关系
- Author:
Yuedan WANG
1
;
Xiangxue MA
;
Beihua ZHANG
;
Jiali LIU
;
Ting CHEN
;
Xiaolan YIN
;
Fengyun WANG
;
Xudong TANG
Author Information
1. 中国中医科学院西苑医院脾胃病研究所，北京 100091
- Keywords:
Gastrointestinal diseases;
Overlap of symptoms;
Holism of five organs;
Exosome
- From:
International Journal of Traditional Chinese Medicine
2025;47(4):433-438
- CountryChina
- Language:Chinese
-
Abstract:
The theory of "holism of five organs" highly encapsulates the understanding of TCM on the integrity, connectivity, and unity of the internal life functions and morphological structures of the human body. Functional gastrointestinal disorders (FGIDs) frequently overlap, and TCM has significant advantages in their prevention and treatment based on the theory of the holistic view and syndrome differentiation and treatment. Exosomes are extracellular vesicles whose secretory form and biological functions fully reflect the "holism of five organs", and they are of great value in the pathogenesis, diagnosis and treatment of overlap of symptoms of FGIDs. This article interpreted the relationship between exosomes and overlap of symptoms of FGIDs with the "holism of five organs", aiming to provide new ideas and methods for the prevention and treatment of overlap of symptoms of FGIDs, as well as partly explain the scientific connotation of the theory of "holism of five organs".
