To explore the rule of diagnosis and treatment of chronic heart failure from "disease - syndrome - symptom - stage - molecular phenotype"
10.3760/cma.j.cn115398-20240305-00051
- VernacularTitle:从“病-证-症-期-分子表型”探讨慢性心力衰竭的诊治规律
- Author:
Kun LIAN
1
;
Lichong MENG
;
Ying DENG
;
Zhenyu ZHAO
;
Lin LI
;
Zhixi HU
Author Information
1. 湖南中医药大学中医学院2024级博士研究生,长沙 410208
- Keywords:
Heart failure;
Rules of diagnosis and treatment;
Traditional Chinese Medicine syndrome;
Molecular phenotype;
Combination of disease and syndrome
- From:
International Journal of Traditional Chinese Medicine
2025;47(2):150-156
- CountryChina
- Language:Chinese
-
Abstract:
It is of great significance to study the diagnosis, prevention and treatment of chronic heart failure. This study took the name of Western medicine disease as the main line, took TCM syndromes as the aim, combined the symptoms, signs, stages and molecular phenotype, and explored the diagnosis and treatment law of the disease. It is believed that chronic heart failure includes the syndrome of qi deficiency and blood stasis, yang deficiency and blood stasis, qi-yin deficiency, heart-kidney yang deficiency and yang deficiency water syndrome. There were many clinical manifestations such as chest tightness, shortness of breath, fatigue, limb edema and pulse knot. It involved many pathological mechanisms and molecular phenotype such as myocardial fibrosis, inflammatory response and myocardial cell injury. Treatment should be divided into early, middle and late stages according to the characteristics of "disease - syndrome - symptom- stage- molecular phenotype".