Research progress in the mechanism of TCM regulating intestinal flora imbalance for the treatment of rheumatoid arthritis
10.3760/cma.j.cn115398-20240122-00268
- VernacularTitle:中药调控肠道菌群治疗类风湿关节炎机制研究进展
- Author:
Lilai XING
1
;
Jun LIU
;
Yaoyao SUN
;
Hao WU
;
Chen LI
;
Qiumei DONG
;
Hua HAO
Author Information
1. 内蒙古医科大学2022级硕士研究生，呼和浩特 010000
- Keywords:
Arthritis, rheumatoid;
Intestinal flora;
Chinese materia medica;
Review
- From:
International Journal of Traditional Chinese Medicine
2025;47(2):281-285
- CountryChina
- Language:Chinese
-
Abstract:
Intestinal flora imbalance is closely related to the pathogenesis of rheumatoid arthritis (RA). The existing studies have explored the monomer components such as tripterygium glycosides, total glycosides of Chaenomeles speciosa, and triterpenoid saponins of Clematis, Chinese materia medica such as Tripterygium wilfordii, Caulis Sinomenii, Radix Paeoniae Alba, Fructus Gardeniae, Fructus Chebulae, Radix Ginseng, Radix et Rhizoma Rhei, Rhizoma Atractylodis Macrocephalae, Pterostilbene, and Ginger, as well as the mechanisms of Danggui Sini Decoction, Danggui Niantong Decoction, Duhuo Jisheng Decoction, Yunpi Jiedu Tongluo Qushi Decoction, Qingre Huoxue Decoction, Compound Fengshining, Qingre Yangyin Chushi Decoction, Aconitum Decoction, Zhijing Powder, Jinwu Jiangu Capsule, and Fermented Chinese Medicine Qushi Chubi Decoction in intervening RA by regulating intestinal flora, suggesting that Chinese materia medica can restore intestinal homeostasis, reduce joint inflammation and play a role in the prevention and treatment of RA by regulating immune response, improving intestinal mucosal barrier and regulating intestinal metabolites.
