Study on the medication law for threatened irritability in ancient gynecological monographs based on data mining
10.3760/cma.j.cn115398-20240102-00008
- VernacularTitle:基于数据挖掘的妇科古籍胎动不安用药规律研究
- Author:
Chaonan WANG
1
;
Shunxin JI
;
Xiaoling FENG
;
Wei LI
Author Information
1. 黑龙江中医药大学2022级硕士研究生，哈尔滨 150040
- Keywords:
Threatened atbortion;
Data mining;
Medication law;
Ancient gynecological monographs
- From:
International Journal of Traditional Chinese Medicine
2025;47(1):102-107
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the medication law for threatened irritability in ancient gynecological monographs based on data mining.Methods:Based on Zhong Hua Yi Dian (5th edition), Chinese Medicine Resource Network and the paper version of ancient books, the representative gynecological monographs from the pre-Qin to the Qing Dynasty were selected to retrieve the prescriptions for the treatment of fetal irritability and establish a database. Excel 2019, IBM SPSS Modeler 18.0 and IBM SPSS Statistics 26.0 software were used to perform frequency statistics, association rule analysis and clustering analysis on the data of Chinese materia medica, analyze the core drug groups, and explore the medication laws. Results:A total of 151 prescriptions were included, including 7 kinds of TCM syndrome types, involving 111 kinds of Chinese materia medica. The most commonly used Chinese materia medica were Angelicae Sinensis Radix, Glycyrrhizae Radix et Rhizoma, Atractylodis Macrocephalae Rhizoma, Chuanxiong Rhizoma, and Paeoniae Radix Alba, etc. The efficacy categories were mainly tonic, heat-clearing, blood-activating and stasis-resolving; the medicinal properties were mainly warm and neutral; the tastes were mainly sweet and pungent; the main meridians were spleen, lung, liver and kidney meridians. 17 commonly used TCM combinations were obtained by association rule analysis, and five core TCM combinations were obtained by clustering analysis.Conclusions:In the treatment of threatened irritability, ancient doctors used the method of tonifying kidney and invigorating spleen, tonifying qi and nourishing blood, clearing heat and preventing miscarriage flexibly. The core drugs were mainly Angelicae Sinensis Radix, which was mostly modified on the basic prescriptions such as Siwu Decoction and Jiaoai Decoction.
