Research progress in the mechanism of TCM in the treatment of breast cancer based on signaling pathway
10.3760/cma.j.cn115398-20240125-00320
- VernacularTitle:基于信号通路的中药治疗乳腺癌作用机制研究进展
- Author:
Xiaoya WANG
1
;
Fangzheng JIAO
;
Jing WEI
;
Fang LIU
;
Yanfang PAN
;
Yan FANG
Author Information
1. 陕西中医药大学基础医学院,咸阳 712046
- Keywords:
Carcinoma;
Breast cancer;
TCM;
Signaling pathway;
Research progress;
Review
- From:
International Journal of Traditional Chinese Medicine
2025;47(1):137-141
- CountryChina
- Language:Chinese
-
Abstract:
TCM monomer and its compound preparation have significant effect in the treatment of breast cancer, with unique advantages of multi molecule, multi targeting, less adverse reactions, etc. TCM components such as Carthamus tinctorius polysaccharides, peimine, andrographolide, and Bupleurum saponin D can inhibit the malignant progression of breast cancer by modulating signaling pathways including PI3K/Akt, MAPK, Wnt, and JAK/STAT.