Novel therapeutic strategies: targeting cancer metastasis
10.3760/cma.j.cn371439-20240811-00089
- VernacularTitle:靶向肿瘤转移的新策略
- Author:
Baihong ZHANG
1
;
Hongyun YUE
Author Information
1. 解放军联勤保障部队第九四〇医院肿瘤科，兰州 730050
- Keywords:
Neoplasms;
Neoplasm metastasis;
Therapeutics
- From:
Journal of International Oncology
2025;52(8):528-531
- CountryChina
- Language:Chinese
-
Abstract:
Tumor-related death is often associated with tumor metastasis. Metastasis process includes the acquisition of dissemination traits of tumor cells, dormancy awakening, and distant growth. Changing dissemination traits of cancer cells, maintaining and killing dormant tumor cells, editing pre-metastatic microenvironment, and reprogramming hallmarks of cancer will be key to block tumor metastasis. Bevacizumab, denosumab and cilengitide have been approved for clinical therapies. Tumor screening based on blood tests combined with artificial intelligence will provide new targeted metastasis strategies for clinical treatment.
