Advances in the clinical and translational applications of breast cancer organoids
10.3760/cma.j.cn371439-20250110-00064
- VernacularTitle:乳腺癌类器官在临床及转化应用中的进展
- Author:
Lixi LI
1
;
Boshi DUAN
;
Haili QIAN
;
Fei MA
Author Information
1. 国家癌症中心 国家肿瘤临床医学研究中心 中国医学科学院北京协和医学院肿瘤医院内科，北京 100021
- Keywords:
Breast neoplasms;
Organoids;
Drug evaluation, preclinical;
Precision medicine
- From:
Journal of International Oncology
2025;52(6):379-381
- CountryChina
- Language:Chinese
-
Abstract:
Breast cancer organoids faithfully reflect the structural and functional characteristics of primary tumors, demonstrating broad application potential. Clinically, organoids have been utilized for drug sensitivity testing, significantly enhancing the precision of personalized treatment strategies. Organoids play a crucial role in accelerating new drug development, uncovering drug resistance mechanisms, and improving the efficacy of immunotherapy. In-depth analysis of the application of breast cancer organoid technology in clinical and transformation can provide new ideas for clinical diagnosis and treatment of breast cancer.
