Research progress of the correlation between angiogenesis and osteosarcoma
10.3760/cma.j.cn371439-20241224-00029
- VernacularTitle:血管生成与骨肉瘤的相关性研究进展
- Author:
Wenxia PU
1
;
Zongzhuo DENG
;
Peixin WANG
;
Qiulan WANG
Author Information
1. 甘肃中医药大学第一临床医学院，兰州 730000
- Keywords:
Osteosarcoma;
Angiogenesis inducing agents;
Endothelial cells
- From:
Journal of International Oncology
2025;52(3):186-189
- CountryChina
- Language:Chinese
-
Abstract:
Osteosarcoma is a kind of mesenchymal tissue tumor, which is highly invasive and metastatic. Pro-angiogenic factors and vascular endothelial cells play key roles in the angiogenesis and metastasis of osteosarcoma, and the interaction between vascular endothelial cells and osteosarcoma cells can affect the growth and metastasis of osteosarcoma. Anti-vascular therapeutics agents for osteosarcoma, including monoclonal antibodies, tyrosine kinase inhibitors and traditional Chinese medicines, can inhibit the progression of osteosarcoma. An in-depth study of the correlation between osteosarcoma and angiogenesis can provide new ideas for the study of vascularization of osteosarcoma and anti-vascular treatment of osteosarcoma.
