Progress of clinical application of circulating tumor cells in lung cancer

VernacularTitle:循环肿瘤细胞在肺癌中的临床应用进展
Author: Danlei CHEN ¹ ; Junjun DENG ; Miao LI
Author Information

1. 青海大学研究生院，西宁　810000
Keywords: Neoplastic cells, circulating; Lung neoplasms; Liquid biopsy; Diagnosis; Prognosis
From: Journal of International Oncology 2025;52(2):119-123
CountryChina
Language:Chinese
Abstract: Lung cancer is the cancer with the highest incidence of morbidity and mortality in the world, and the number of lung cancer cases in China is also increasing year by year, which seriously threatens the life and health of human beings. Circulating tumor cells (CTCs) refer to the tumor cell that falls off from primary tumor tissue or metastatic focus into the peripheral blood, which is the key to tumor metastasis. Currently, there are various methods for CTCs testing, each with its own advantages and disadvantages. In recent years, there have been numerous studies on the application of CTCs in lung cancer around the world. Further exploration of the progress of clinical application of CTCs in lung cancer can provide a new basis for the role of CTCs in early diagnosis, efficacy assessment and prognostic monitoring of lung cancer.