Research progress of circadian genes in the occurrence, development and chronotherapy of colorectal cancer
10.3760/cma.j.cn371439-20240528-00009
- VernacularTitle:节律基因在结直肠癌发生发展和时辰疗法中的研究进展
- Author:
Haifeng ZHAN
1
;
Zixuan TAN
;
Wenxue WANG
;
Jiawei GENG
Author Information
1. 昆明理工大学附属医院/云南省第一人民医院感染性疾病及肝病科，昆明 650500
- Keywords:
Circadian rhythm;
Colorectal neoplasms;
Clock gene
- From:
Journal of International Oncology
2025;52(1):60-64
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, studies have found that the abnormal expression of rhythm genes is closely related to the risk of occurrence and the progression of the disease course of colorectal cancer. In addition, chronotherapy based on the circadian rhythm theory has shown certain effects in the clinical treatment of colorectal cancer, but there are still great limitations. Therefore, it is very important to clarify the mechanism of action of rhythm genes in the occurrence and development of colorectal cancer, which may provide a theoretical basis for the clinical application of chronotherapy.
