Relationship between CCL11 and colorectal cancer
10.3760/cma.j.cn115396-20241022-00324
- VernacularTitle:CCL11与结肠癌相关性概述
- Author:
Yanjie ZHAO
1
;
Jianyu WU
Author Information
1. 哈尔滨医科大学附属第一医院甲状腺外科，哈尔滨 150007
- Keywords:
Chemokine CCL11;
Colonic neoplasms;
Neoplasm metastasis;
Prognosis
- From:
International Journal of Surgery
2025;52(5):338-342
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer is a common malignant tumor disease that poses a threat to human life. Its early stage is relatively concealed and often does not present specific clinical manifestations. Therefore, metastasis is the main factor leading to death. However, for colorectal cancer and all other tumor diseases, early identification and intervention have a significant impact on the prognosis, survival time and quality of life of patients. However, the current clinical examination and testing methods all have certain limitations, especially in terms of the sensitivity and specificity for indicating tumor occurrence and metastasis, which still need to be improved. Therefore, finding new biomarkers is of great significance, and the discovery of new biomarkers can also increase the risk stratification of screening. In recent years, with the deepening of research, chemokine CCL11 has gradually come into researchers′ view. CCL11 is an eosinophil chemotactic factor and was first reported in guinea pig allergic airway inflammation. With the progress of research, its important role in many tumor-related diseases has gradually emerged. This article will provide an overview of the correlation between CCL11 and colon cancer.
