Research progress on preparation, applications, and integration with artificial intelligence of spinal cord organoids
10.3760/cma.j.cn121382-20250724-00057
- VernacularTitle:脊髓类器官制备、应用及与人工智能结合的研究进展
- Author:
Can LIANG
1
;
He SHEN
Author Information
1. 中国医学科学院 北京协和医学院生物医学工程研究所,天津 300192
- Keywords:
Spinal cord injury;
Spinal cord organoids;
Artificial intelligence;
Drug screening;
Regenerative repair
- From:
International Journal of Biomedical Engineering
2025;48(5):507-515
- CountryChina
- Language:Chinese
-
Abstract:
Spinal cord organoids are three-dimensional in vitro models constructed using stem cell-based techniques. These models are capable of approximating the tissue structure, developmental processes, and physiological functions of the human spinal cord. These spinal cord organoids have demonstrated significant potential in areas such as disease modeling, drug screening, and regenerative medicine. In this review, the preparation methods and application scenarios of spinal cord organoids were systematically reviewed, and innovatively integration with artificial intelligence were discussed. The aim of this review is to provide a reference for innovative development and practical application in this field.