Research progress of vitrification cryopreservation technology
10.3760/cma.j.cn121382-20250415-00030
- VernacularTitle:玻璃化冷冻保存技术的研究进展
- Author:
Xinyi ZHAO
1
;
Shufang WEN
;
Rongrong WEI
;
Fei GE
;
Yi LIU
Author Information
1. 首都医科大学附属北京胸科医院（北京市结核病胸部肿瘤研究所）生物样本与数据资源库，北京 101149
- Keywords:
Vitrification cryopreservation;
Cryoprotectant;
Carrier;
Organ preservation
- From:
International Journal of Biomedical Engineering
2025;48(4):407-412
- CountryChina
- Language:Chinese
-
Abstract:
Vitrification cryopreservation technology converts the liquid water in biological samples into glassy solids through ultra-rapid cooling. In this review, the core research of vitrification cryopreservation technology was mainly reviewed, such as the optimization of cryoprotectant formulations, the improvements to temperature control methods, the innovative carrier designs and the improvements to rewarming technology. The application status and issues in the fields of organ preservation, tumor research, reproductive medicine and rare cell preservation were also summarized. By combining the technical principles with glassy state detection methods, a theoretical basis was provided for optimizing the technical system and expanding application scenarios, thereby promoting its large-scale application in clinical and biological sample libraries.
