Research progress of repetitive transcranial magnetic stimulation in regulating neural electrical activity in early Alzheimer′s disease
10.3760/cma.j.cn121382-20250414-00029
- VernacularTitle:重复经颅磁刺激调控早期阿尔茨海默病神经电活动的研究进展
- Author:
Xinru LI
1
;
Ruru WANG
;
Zhipeng LIU
;
Tao YIN
;
Xin WANG
Author Information
1. 天津体育学院运动健康学院 天津市运动生理学与运动医学重点实验室，天津 300381
- Keywords:
Alzheimer′s disease;
Repetitive transcranial magnetic stimulation;
Nerve oscillations;
Neuronal firing
- From:
International Journal of Biomedical Engineering
2025;48(3):288-294
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer′s disease (AD) is a degenerative disorder of the central nervous system. In the early stages of AD, i.e. when cognitive impairment is mild or absent but biomarkers are present, patients show abnormal neuroelectric activity. Repetitive transcranial magnetic stimulation (rTMS) is an important method of non-invasively regulating neuroelectric activity in the brain. It does so by inducing microcurrents to change the membrane potential of nerve cells in the brain based on electromagnetic induction. In this review, the characteristics of neuroelectric activity of AD patients and AD model mice in the early stage of AD were mainly introduced, and the regulation of rTMS on the neuroelectric activity of early AD was discussed.
