Application progress of nano drug delivery systems in the treatment of colitis
10.3760/cma.j.cn121382-20241101-00201
- VernacularTitle:纳米药物递送系统在结肠炎治疗中的应用进展
- Author:
Yifan ZHANG
1
;
Linhua ZHANG
;
Dunwan ZHU
Author Information
1. 中国医学科学院 北京协和医学院生物医学工程研究所，天津 300192
- Keywords:
Colitis;
Nano drug delivery systems;
Organic polymers;
Inorganic materials;
Outer membrane vesicles;
Exosomes;
Metal-organic frameworks
- From:
International Journal of Biomedical Engineering
2025;48(2):105-111
- CountryChina
- Language:Chinese
-
Abstract:
Colitis is a common intestinal disease characterized by a chronic course, impaired quality of life and poor prognosis. Due to the anatomical specificity of the colon, the development of targeted and efficient drug delivery systems has become a research focus. With the rapid development of nanotechnology, nano drug delivery systems have been widely used in colitis treatment owing to their ease of preparation, controllable quality and excellent targeting capability. In this review, the general situation of colitis was summarized. Based on the classification of drug delivery carriers of different materials, the application progress of organic polymers, inorganic materials, biological and metallic nano drug delivery systems in colitis therapy was introduced. The potential of these four types of nano drug delivery systems was summarized and analyzed.
