Cerebral autoregulation in cerebral small vessel disease
10.3760/cma.j.issn.1673-4165.2025.05.011
- VernacularTitle:脑小血管病的脑血流自动调节
- Author:
Furong LI
1
;
Ya'nan ZHANG
;
Shuhan LIU
;
Weiwei DONG
;
Xiaowen SUI
;
Xin PAN
;
Hongling ZHAO
Author Information
1. 大连理工大学附属中心医院(大连市中心医院)脑卒中中心,大连 116000
- Keywords:
Cerebral small vessel diseases;
Magnetic resonance imaging;
Cerebrovascular circulation;
Neurovascular coupling
- From:
International Journal of Cerebrovascular Diseases
2025;33(5):383-386
- CountryChina
- Language:Chinese
-
Abstract:
Cerebral blood flow directly affects the metabolism of substances and neural activity in the brain, and is closely associated with the occurrence and development of cerebral small vessel disease (CSVD). Multiple studies have revealed that various imaging biomarkers in patients with CSVD, such as lacunar infarction, enlarged perivascular spaces, cerebral microbleeds, cerebral atrophy, and white matter hyperintensities, are closely associated with cerebral autoregulation (CA) function. Therefore, understanding the regulatory mechanism of CA in patients with CSVD is of great significance for delaying the further development of CSVD, improving cerebral ischemia and cognitive impairment. This article reviews the correlation and mechanism between CA and CSVD.