Application of omega-3 polyunsaturated fatty acids in the prevention and treatment of ischemic stroke
10.3760/cma.j.issn.1673-4165.2025.04.008
- VernacularTitle:ω-3多不饱和脂肪酸在缺血性卒中防治中的应用
- Author:
Ruiping ZHANG
1
;
Huakun LIU
;
Jianfeng CHU
Author Information
1. 济宁医学院,济宁 272067
- Keywords:
Ischemic stroke;
Fatty acids, omega-3;
Eicosapentaenoic acid;
Docosahexaenoic acids;
Dietary supplements
- From:
International Journal of Cerebrovascular Diseases
2025;33(4):282-286
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, the role of omega-3 polyunsaturated fatty acids (n-3 PUFAs) in the prevention and treatment of ischemic stroke has received widespread attention. Researches have shown that n-3 PUFAs can reduce the risk of stroke and improve stroke outcome through various mechanisms, including anti-inflammatory, antioxidant, improvement of endothelial function, promotion of angiogenesis, and anti-apoptotic effects, demonstrating potential in the prevention and treatment of ischemic stroke. This article reviews the mechanism of action and clinical research of n-3 PUFAs in ischemic stroke.