Role of interleukin-33/ST2 in ischemic stroke
10.3760/cma.j.issn.1673-4165.2025.04.007
- VernacularTitle:白细胞介素-33/ST2在缺血性卒中中的作用
- Author:
Dongzhu WEI
1
;
Yongjiu WANG
Author Information
1. 山东第二医科大学附属青岛医院（青岛市第八人民医院）神经内科，青岛 266121
- Keywords:
Ischemic stroke;
Interleukin-33;
Interleukin-1 receptor-like 1 protein;
Signal transduction;
Neuroprotection
- From:
International Journal of Cerebrovascular Diseases
2025;33(4):277-281
- CountryChina
- Language:Chinese
-
Abstract:
Ischemic stroke is a serious nervous system disease characterized by high incidence, high disability and high mortality. Researches have shown that the interleukin-33/ST2 pathway plays a critical role in the pathophysiological process of stroke. This article summarizes the role and mechanism of the IL-33/ST2 pathway in ischemic stroke, as well as its potential as a therapeutic target, hopping to provide new treatment strategies for ischemic stroke.
