Predictive value of C-reactive protein/albumin ratio and fibrinogen/albumin ratio in patients with acute ischemic stroke
10.3760/cma.j.issn.1673-4165.2025.03.007
- VernacularTitle:C反应蛋白/白蛋白比值和纤维蛋白原/白蛋白比值在急性缺血性卒中患者中的预测价值
- Author:
Yujie WANG
1
;
Shouzhen LUO
;
Minghua WU
;
Zhaoyao CHEN
Author Information
1. 南京中医药大学附属医院神经内科，南京 210002
- Keywords:
Ischemic stroke;
C-reactive protein;
Fibrinogen;
Serum albumin;
Inflammation;
Treatment outcome;
Biomarkers
- From:
International Journal of Cerebrovascular Diseases
2025;33(3):199-205
- CountryChina
- Language:Chinese
-
Abstract:
Acute ischemic stroke (AIS) is one of the leading causes of death and disability in the global population, and its pathological mechanism is closely associated with inflammation and coagulation-nutrient imbalance. The C-reactive protein/albumin ratio (CAR) and fibrinogen/albumin ratio (FAR), as novel composite inflammatory markers, provide more comprehensive outcome prediction tools in patients with AIS by integrating information on systemic inflammation severity and nutritional status. This article reviews the clinical value of CAR and FAR in predicting early neurological deterioration, hemorrhagic transformation, stroke associated pneumonia, and poor outcome in patients with AIS, providing a scientific basis for optimizing early risk stratification and clinical intervention in patients with AIS.
