Onset-to-puncture time in patients with stroke undergoing endovascular treatment: influencing factors and optimization strategies
10.3760/cma.j.issn.1673-4165.2025.02.006
- VernacularTitle:接受血管内治疗的卒中患者发病至股动脉穿刺时间：影响因素和改进策略
- Author:
Fangjing LIN
1
;
Shiyu HU
;
Lijie REN
Author Information
1. 深圳大学医学部，深圳 518060
- Keywords:
Ischemic stroke;
Endovascular procedures;
Thrombectomy;
Time-to-treatment;
Emergency medical services;
Patient transfer;
Workflow;
Time factor;
Treatment outc
- From:
International Journal of Cerebrovascular Diseases
2025;33(2):113-120
- CountryChina
- Language:Chinese
-
Abstract:
Endovascular therapy (EVT) is the standard treatment for acute ischemic stroke (AIS) due to large vessel occlusion (LVO), which can effectively improve patient outcome by timely restoring cerebral blood flow perfusion. The benefits of EVT are time-dependent and significant when initiated within 6 hours of onset. The onset-to-puncture time (OPT) is divided into onset-to-door time (ODT) and door-to-puncture time (DPT). ODT is the time from symptom onset to arrival at the emergency department, reflecting the efficiency of prehospital emergency treatment; DPT is the time from emergency admission to completion of femoral artery puncture, reflecting the efficiency of in-hospital diagnosis and treatment. Despite various efforts were made in the early stage to enable 41.6% of patients with AIS who received EVT achieved a door-to-device time (DDT) of <120 min, OPT is still not ideal, and issues such as inaccurate prehospital assessments and delayed in-hospital diagnosis and treatment remain severe. This article elaborates on the impact and possible mechanisms of OPT on the outcome of patients with AIS undergoing EVT, and discusses the influencing factors and optimization strategies of OPT.
