Correlation between high-resolution MRI features of spontaneous vertebral artery dissection and ischemic stroke
10.3760/cma.j.issn.1673-4165.2024.10.004
- VernacularTitle:自发性椎动脉夹层的高分辨率MRI影像学特征与缺血性卒中的相关性
- Author:
Xiaoxiao NIE
1
;
Linlin CHAO
;
Mengmeng CAI
;
Jingjing SHI
;
Jianhua ZHAO
Author Information
1. 郑州大学人民医院（河南省人民医院）神经内科，郑州 450003
- Keywords:
Vertebral artery dissection;
Ischemic stroke;
Magnetic resonance imaging;
Risk factors
- From:
International Journal of Cerebrovascular Diseases
2024;32(10):741-746
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the high-resolution MRI (HR-MRI) features and its correlation with ischemic stroke in patients with spontaneous vertebral artery dissection (sVAD).Methods:Consecutive patients with sVAD admitted to the People's Hospital of Zhengzhou University from January 2017 to January 2024 were included retrospectively. They were divided into stroke group and non-stroke group based on whether ischemic stroke was present or not. The vascular risk factors, clinical manifestations, vascular segments involved and HR-MRI features of the two groups were compared. Multivariate logistic regression analysis was used to determine the independent risk factors for ischemic stroke in patients with sVAD. Results:A total of 103 patients with sVAD were enrolled, including 59 males (57.3%), aged 46.40±3.73 years. 40 patients (38.8%) had concurrent stroke, while 63 (61.2%) did not. The proportion of patients with intramural hematoma, intramural hematoma T 1 isointensity, severe stenosis or occlusion, and intracranial segment involvement in the stroke group were significantly higher than those in the non-stroke group (all P<0.05). Multivariate logistic regression analysis suggests that severe stenosis or occlusion (odds ratio 2.623, 95% confidence interval 1.068-6.440; P=0.035) and intramural hematoma (odds ratio 2.842, 95% confidence interval 1.134-7.118; P=0.026) were the independent risk factors for ischemic stroke. Conclusions:Severe stenosis or occlusion and intramural hematoma shown by HR-MRI are the independent risk factors for ischemic stroke in patients with sVAD. Early identification of these factors may help with early intervention.
