Progress in research on the role of DNA methylation in cervical cancer
10.3969/j.issn.1673-4130.2025.20.018
- VernacularTitle:DNA甲基化在宫颈癌中作用的研究进展
- Author:
Xueqi SUN
1
;
Fang CUI
Author Information
1. 重庆医科大学附属第一医院检验科,重庆 400016
- Keywords:
cervical cancer;
DNA methylation;
screening;
prognosis
- From:
International Journal of Laboratory Medicine
2025;46(20):2533-2539
- CountryChina
- Language:Chinese
-
Abstract:
Cervical cancer poses a significant threat to women's health worldwide,and its early detection is crucial for improving treatment outcomes and reducing mortality rates.DNA methylation,as a stable epigenet-ic marker,plays a significant role in the occurrence and development of cervical cancer.The combination of methylation markers with traditional screening methods has been shown to achieve high sensitivity and speci-ficity.This article provides a concise review of the potential,challenges,and future developments of DNA methylation in cervical cancer screening,as well as how these molecular markers can facilitate more precise risk stratification and personalized management of cervical cancer.
