Research progress on biomarkers related to the diagnosis and prognosis of multiple myeloma
10.3969/j.issn.1673-4130.2025.17.018
- VernacularTitle:多发性骨髓瘤诊断及预后相关生物标志物的研究进展
- Author:
Han QI
1
;
Bin YIN
Author Information
1. 江南大学附属中心医院:检验科,江苏 无锡 214002
- Keywords:
multiple myeloma;
biomarkers;
molecular diagnosis;
prognostic markers
- From:
International Journal of Laboratory Medicine
2025;46(17):2148-2152
- CountryChina
- Language:Chinese
-
Abstract:
Multiple myeloma(MM)is a common hematological malignancy that is currently incurable.MM exhibits significant heterogeneity in its manifestations,genetics,and response to treatment.Although some traditional biomarkers and drug combination therapies used for MM diagnosis and evaluation have a-chieved certain results,the recurrence and mortality rates of the disease are still high,and the prognosis is poor.Therefore,it is crucial to explore more sensitive and effective diagnostic and prognostic biomarkers.This article focuses on introducing new biomarkers reported and studied in recent years,which may facilitate early diagnosis,prognostic stratification,and personalized treatment decisions for MM.