Analysis of nucleic acid detection results of 13 respiratory pathogens in 11 065 cases
10.3969/j.issn.1673-4130.2025.17.004
- VernacularTitle:11 065例13种呼吸道病原体核酸检测结果分析
- Author:
Shaowei LIU
1
;
Jun LUO
;
Qingyong ZHANG
Author Information
1. 三峡大学第一临床医学院(宜昌市中心人民医院)检验科,湖北 宜昌 443003
- Keywords:
respiratory pathogens;
infection status;
epidemic prevention and control
- From:
International Journal of Laboratory Medicine
2025;46(17):2069-2072
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the epidemiological characteristics of respiratory pathogens among the population in the region,and provide reference for epidemic prevention and control.Methods A total of 11 065 patients who visited the hospital from March 2023 to February 2024 due to respiratory infections and underwent nucleic acid testing for 13 respiratory pathogens were selected.The infection status and epidemio-logical characteristics of pathogens in people with different genders,and ages,and in different seasons were an-alyzed.Results The total positive rate of nucleic acid detection of 13 respiratory pathogens in 11 065 patients was 57.05%,and the infections were mainly caused by single pathogen and two pathogens.The positive rate of males was 56.53%,the positive rate of females was 57.73%,and there was no statistically significant difference in positive rates between males and females(P>0.05).The positive rates of infant group(79.20%),preschool group(79.57%),and adolescent group(70.18%)were significantly higher than those of middle-aged and young group(35.61%)and elderly group(32.26%,P<0.05).The positive rates in spring,summer,autumn,and winter were 43.34%,49.91%,64.69%,and 59.80%,respectively,with statisti-cally significant differences(P<0.05),and the positive rates were higher in autumn and winter.The top five positive rates of 13 respiratory pathogens were mycoplasma pneumoniae(MP),human rhinovirus(HRV),in-fluenza A virus(Flu A),respiratory syncytial virus(RSV),human metapneumovirus nucleic acid(HMPV).Conclusion Respiratory pathogen infections in the region are mainly caused by single pathogen and two pathogens.The high-risk population for infection is infants,preschool children,and adolescents.The high inci-dence seasons for infection are autumn and winter.The pathogens with high incidence of infection are MP,HRV,Flu A,RSV,HMPV,etc.
