The predictive value of thromboelastography combined with serum D-D and TBIL for postoperative DVT in patients with hip fracture
10.3969/j.issn.1673-4130.2025.16.010
- VernacularTitle:血栓弹力图联合血清D-D、TBIL对髋骨骨折患者术后发生DVT的预测价值
- Author:
Shengxia ZHAO
1
;
Jinping SONG
;
Peipei LU
Author Information
1. 新疆维吾尔自治区人民医院临床检验中心,新疆乌鲁木齐 830000
- Keywords:
thromboelastography;
D-dimer;
total bilirubin;
deep vein thrombosis
- From:
International Journal of Laboratory Medicine
2025;46(16):1973-1977,1983
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the predictive value of thromboelastography(TEG)combined with ser-um D-dimer(D-D)and total bilirubin(TBIL)in the risk of postoperative deep vein thrombosis(DVT)in pa-tients with hip fracture.Methods A total of 120 patients with hip fracture who underwent surgical treatment in this hospital from January 2022 to January 2024 were retrospectively selected.According to the occurrence of postoperative DVT,the patients were divided into DVT group(n=34)and non-DVT group(n=86).The TEG parameters[coagulation reaction time(R),blood clot formation time(K),α angle and maximum ampli-tude of thrombus(MA)],D-D and TBIL levels were compared between the two groups before operation.Mul-tivariate Logistic regression was used to analyze the influencing factors of postoperative DVT in patients with hip fracture.Receiver operating characteristic(ROC)curve was used to analyze the predictive value of TBIL,D-D and TEG parameters for postoperative DVT in patients with hip fracture.Results Compared with the non-DVT group,the TBIL level,R value and K value in the DVT group were significantly decreased,while the D-D level,α angle and MA value were significantly increased(P＜0.05).Multivariate Logistic regression anal-ysis showed that TBIL,D-D and TEG parameters were the influencing factors of postoperative DVT in pa-tients with hip fracture(P＜0.05).ROC curve results showed that the area under the curve of TBIL,D-D,TEG parameters combined to predict postoperative DVT in patients with hip fracture was 0.940,the sensitivi-ty was 82.4％,and the specificity was 93.0％.Conclusion TEG combined with D-D and TBIL levels have a high predictive value in postoperative DVT in patients with hip fracture,which can be used in the early evalua-tion of postoperative DVT in patients with hip fracture,and help to improve the prognosis of patients.
