Predictive value of ESR,CRP and IL-34 for unplanned readmission of patients with bronchial tuberculosis underwent initial treatment
10.3969/j.issn.1673-4130.2025.10.010
- VernacularTitle:ESR、CRP、IL-34对初治支气管结核患者非计划再入院的预测价值
- Author:
Jing HUI
1
;
Abduweili CARDILIA
;
Xiaohui WEI
;
RE YIHAN GULI Aken
Author Information
1. 新疆维吾尔自治区人民医院呼吸与危重症医学中心,新疆乌鲁木齐 830001
- Keywords:
erythrocyte sedimentation rate;
C-reactive protein;
interleukin-34;
bronchial tuberculo-sis;
unplanned readmission;
predictive value
- From:
International Journal of Laboratory Medicine
2025;46(10):1201-1205,1211
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the predictive value of erythrocyte sedimentation rate(ESR),C-reactive protein(CRP),and interleukin-34(IL-34)for unplanned readmission in patients with bronchial tuberculosis underwent initial treatment.Methods A total of 156 patients with bronchial tuberculosis underwent initial treatment in Xinjiang Uygur Autonomous Region People's Hospital from January to March 2024 were select-ed,and were assigned into readmission group(n=27)and non-readmission group(n=129)according to the presence or absence of unplanned readmission within 30 d of discharge from the hospital.The clinical data were collected in all patients.ESR,CRP,and IL-34 were measured within 24 h at admission.The influencing factors of unplanned readmission in patients with bronchial tuberculosis underwent initial treatment were i-dentified using Multivariate Logistic regression analysis.Then the predictive value of ESR,CRP,and IL-34 for unplanned readmission was evaluated using the receiver operating characteristics(ROC)curve.Results The percentage of patients with age ≥60 years,comorbid diabetes mellitus,and first length of stay＞6 d was high-er in readmission group than that in non-readmission group(P＜0.05).ESR,CRP,and IL-34 levels were higher in readmission group than in non-readmission group(P＜0.05).Multivariate Logistic regression analy-sis showed that age ≥60 years,comorbid diabetes mellitus,first length of stay＞6 d,high ESR,high CRP,and high IL-34 were risk factors for unplanned readmission in patients with bronchial tuberculosis underwent ini-tial treatment(P＜0.05).ROC curve analysis indicated that the difference between the area under the curve,specificity and sensitivity of combined test of ESR,CRP,and IL-34 at their cutoff values in the prediction of unplanned readmission in patients with bronchial tuberculosis underwent initial treatment compared to sepa-rate test(P＜0.05).Conclusion ESR,CRP and IL-34 are of great value in predicting the unplanned readmis-sion of patients with bronchial tuberculosis underwent initial treatment,and the predictive efficacy of com-bined test is the best.
