Relationship between monocyte to high-density lipoprotein cholesterol ratio and atrial fibrillation in diabetes mellitus patients
10.3969/j.issn.1673-4130.2025.08.008
- VernacularTitle:单核细胞与高密度脂蛋白胆固醇比值与糖尿病合并心房颤动的关系研究
- Author:
Ruihuan ZHANG
1
;
Yurong LIAN
Author Information
1. 长治医学院第一临床学院,山西长治 046013;山西医科大学第七临床医学院附属临汾市人民医院心血管内科,山西临汾 041000
- Keywords:
atrial fibrillation;
diabetes mellitus;
monocyte to high-density lipoprotein cholesterol ratio
- From:
International Journal of Laboratory Medicine
2025;46(8):937-942
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between the monocyte to high-density lipoprotein choles-terol ratio(MHR)and atrial fibrillation(AF)in diabetes mellitus(DM)patients by analyzing the clinical da-ta.Methods A total of 132 patients diagnosed with DM in Linfen People's Hospital,the Seventh Clinical Col-lege of Shanxi Medical University from January 2018 to December 2023 were selected as group A,and 139 pa-tients with DM complicated with AF were selected as group B.The clinical data of the two groups were com-pared,and multivariate Logistic regression analysis was applied to identify the influencing factors of DM com-plicated with AF.The diagnostic value of MHR for AF in DM patients was evaluated by receiver operating characteristic(ROC)curve.Results There were statistically significant differences in age,hypertension,coro-nary heart disease,platelet count,neutrophils,lymphocytes,mean red blood cell volume,red blood cell volume distribution width,total bilirubin,conjugated bilirubin,unconjugated bilirubin,high-density lipoprotein choles-terol,neutrophil to lymphocyte ratio,and MHR between group A and group B(P＜0.05).The results of mul-tivariate Logistic analysis showed that MHR,age,hypertension,and coronary heart disease were independent risk factors for DM patients with AF(P＜0.05).ROC curve analysis showed that the area under the curve of MHR and the combination of age and MHR for diagnosing DM complicated with AF were 0.578(95％CI:0.510-0.646)and 0.811(95％CI:0.759-0.862),respectively.Conclusion MHR is an independent risk fac-tor for DM complicated with AF,and has good diagnostic value combined with age,which can be used to as-sess the risk of the occurrence of AF in the clinical management of DM patients.
