Research progress of GNB2 protein
10.3969/j.issn.1673-4130.2025.05.021
- VernacularTitle:GNB2蛋白的研究进展
- Author:
Li XIONG
1
;
Lihong YANG
;
Yuxin FAN
;
Huan DENG
;
Yin XIANG
;
Yang YANG
Author Information
1. 乐山市人民医院检验科,四川 乐山 614000
- Keywords:
guanylate binding protein subunit β-2;
cell signaling transduction;
regulation mechanisms
- From:
International Journal of Laboratory Medicine
2025;46(5):616-619
- CountryChina
- Language:Chinese
-
Abstract:
Guanylate binding protein subunit β-2(GNB2)is an important part of G protein family.In the process of cell signal transduction,GNB2 plays a structural support and regulatory role in G protein complex,ensuring the correct transmission and amplification of signals,interacting with receptors and regulating vari-ous effector enzymes and ion channels,and mediating a variety of physiological functions.Therefore,GNB2 plays a key role in cell signaling,and participates in the regulation of cell proliferation,differentiation and mi-gration and other biological processes.This article reviews the research progress of GNB2,focusing on its structure,function,regulatory mechanism,disease correlation and importance in tumor research.
