Overview and prospects of diagnostic methods for bone metastasis of breast cancer,prostate cancer and lung cancer
10.3969/j.issn.1673-4130.2025.03.020
- VernacularTitle:乳腺癌、前列腺癌及肺癌骨转移的诊断方法概述及展望
- Author:
Fei DING
1
;
Yong HE
;
Xin NIE
;
Guixing LI
Author Information
1. 四川大学华西医院实验医学科,四川成都 610041
- Keywords:
bone metastasis;
imaging examination;
biomarker
- From:
International Journal of Laboratory Medicine
2025;46(3):354-359
- CountryChina
- Language:Chinese
-
Abstract:
Bone metastasis is a serious complication in the course of malignant tumors and has a poor prog-nosis.The incidence of breast cancer,prostate cancer and lung cancer is the highest.A highly sensitive and highly specific test method for the early diagnosis of malignant bone metastases of these tumors,which is es-sential for reducing the incidence of bone-related events and improving the prognosis of patients with malig-nant tumors,is urgently needed.At present,the diagnosis of bone metastasis in patients with malignant tumors mainly relies on imaging.However,due to limitations in the development of imaging technology,its clinical use is still limited by sensitivity,cost-effectiveness,availability,and others.Close clinical follow-up and monitoring of patients diagnosed with malignant tumors are essential for effective patient management.Based on the current literature,this review aims to summarize the early diagnosis and detection methods for bone metastases in breast cancer,prostate cancer and lung cancer,including imaging techniques,pathology,bio-chemistry and molecular methods,and to review the development trends of future diagnostic techniques.
