Research progress of liquid biopsy based on exosomes in tumor diagnosis and treatment
10.3969/j.issn.1673-4130.2025.03.015
- VernacularTitle:基于外泌体的液体活检在肿瘤诊疗中的研究进展
- Author:
Li MAO
1
;
Yao CHENG
;
Qiuqian LIU
Author Information
1. 陆军特色医学中心疾病预防控制科,重庆 400042
- Keywords:
tumor;
exosome;
liquid biopsy
- From:
International Journal of Laboratory Medicine
2025;46(3):329-334
- CountryChina
- Language:Chinese
-
Abstract:
Exosome-based liquid biopsy technology,with its unique advantages,has demonstrated signifi-cant application potential in the field of tumor diagnosis and treatment.This article aims to outline the basic characteristics of exosomes,their extraction and identification techniques,and focuses on the latest research progress of exosomes in the field of tumor diagnosis and treatment.Current studies indicate that the quantity,size of exosomes,and the biomarkers they carry are of great clinical value in achieving personalized medicine,improving the accuracy of early diagnosis,monitoring treatment effects,and assessing prognosis.These aspects hold profound significance for advancing the development of precision medicine in tumors.Although there are still certain challenges in the standardization of exosome isolation and purification,and the diversity of sample processing,with ongoing research and continuous technological development,exosomes are expected to play an even more important role in the field of tumor diagnosis and treatment.
