Analysis of pathogen species and clinical characteristics in patients with acute upper respiratory tract infection
10.3969/j.issn.1673-4130.2025.03.001
- VernacularTitle:急性上呼吸道感染患者病原体种类与临床特征分析
- Author:
Jialiang LI
1
;
Weijin CAO
;
Wenliang TANG
;
Yang YANG
Author Information
1. 南京大学医学院附属金陵医院/东部战区总医院检验科,江苏南京 210002
- Keywords:
acute upper respiratory tract infection;
pathogens;
throat swab;
nucleic acid testing
- From:
International Journal of Laboratory Medicine
2025;46(3):257-260
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the pathogen species and clinical characteristics in patients with acute up-per respiratory tract infection.Methods A total of 275 patients with acute upper respiratory tract infection admitted to Jinling Hospital,Affiliated Hospital of Medical School,Nanjing University from December 1,2023 to May 15,2024 were selected as research objects.Real-time fluorescence quantitative polymerase chain reac-tion was used to detect pathogen species in throat swab samples,and clinical data and peripheral blood test in-dexes were collected in the medical record system.Results The positive detection rate of influenza A virus was 9.45%,influenza B virus 17.82%,respiratory syncytial virus 9.45%,adenovirus 9.21%,severe acute re-spiratory syndrome coronavirus 2 18.37%,mycoplasma pneumoniae 10.04%,and chlamydia pneumoniae 1.67%.Compared with other age groups,the positive detection rates of influenza A virus,influenza B virus,respiratory syncytial virus,adenovirus,mycoplasma pneumoniae and chlamydia pneumoniae in patients<18 years old were higher,and the difference was statistically significant(P<0.05).The proportion of monocytes in patients infected with influenza B virus was higher than that in patients infected with other pathogens,and the difference was statistically significant(P<0.05).Conclusion Identification the pathogen types of acute upper respiratory tract infection patients is helpful for developing appropriate treatment plans and providing a basis for clinical diagnosis and treatment for the patients.
