Value of mean platelet volume/lymphocyte ratio in predicting the occurrence of deep vein thrombosis after artificial hip replacement surgery
10.3969/j.issn.1673-4130.2024.24.013
- VernacularTitle:血小板平均体积/淋巴细胞比值对人工髋关节置换术后深静脉血栓发生的预测价值
- Author:
Ying PU
1
;
Rui ZHANG
;
Lu ZHANG
;
Chenfei YANG
;
Keqin HU
Author Information
1. 川北医学院护理学院,四川南充 637000
- Keywords:
artificial hip replacement surgery;
mean platelet volume/lymphocyte ratio;
deep vein thrombosis
- From:
International Journal of Laboratory Medicine
2024;45(24):3010-3014
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of mean platelet volume/lymphocyte ratio(MPVLR)in predicting the occurrence of deep vein thrombosis(DVT)after artificial hip replacement surgery.Methods A total of 104 patients who underwent artificial hip replacement surgery in Affiliated Hospital of North Sichuan Medical College from November 2022 to November 2023 were selected as the research objects.According to whether or not they had DVT,104 patients were divided into DVT group(36 cases)and non-DVT group(68 cases).The mean platelet volume(MPV)and lymphocyte count(LYC)were measured by automatic blood cell analyzer in all patients after admission,and MPVLR was calculated.Receiver operating characteristic curve was used to analyze the predictive value of MPV,LYC,and MPVLR for the occurrence of DVT after artificial hip replacement surgery.Multivariate Logistic regression analysis was used to explore the influencing factors of DVT after artificial hip replacement surgery.Results MPV and MPVLR in VTE group were higher than those in non-VTE group(P<0.05),and LYC was lower than that in non-VTE group(P<0.05).The area under the curve(AUC)of MPV and LYC for predicting DVT after artificial hip arthroplasty were 0.774(95%CI:0.729-0.824)and 0.851(95%CI:0.806-0.901),respectively.AUC of MPVLR for predicting DVT after artificial hip replacement surgery was 0.943(95%CI:0.898-0.993).The body mass index and the proportion of postoperative bed rest time≥3 days in the DVT group were higher than those in the non-DVT group(P<0.05).Body mass index ≥22.73 kg/m2(OR=1.923,95%CI:1.237-2.989),postoperative bed rest time≥3 days(OR=2.380,95%CI:1.380-4.104),MPV≥9.65 fL(OR=2.563,95%CI:1.548-4.241),LYC≤1.70× 109/L(OR=2.208,95%CI:1.404-3.472),MPVLR≥5.95(OR=2.942,95%CI:1.816-4.764)were the risk factors for DVT after artificial hip replacement surgery(P<0.05).Conclusion High MPVLR is one of the risk factors for DVT after artificial hip replacement surgery.It could be used as an im-portant indicator to predict the occurrence of DVT after artificial hip replacement surgery,and its predictive performance is excellent.