Advances in risk factors and predictive models for childhood IgA vasculitis nephritis
10.3760/cma.j.issn.1673-4408.2025.08.007
- VernacularTitle:儿童IgA血管炎肾炎危险因素及预测模型的研究进展
- Author:
Lingling TIAN
1
;
Yuna BI
Author Information
1. 青岛大学附属山东省妇幼保健院儿科，济南 250014
- Keywords:
IgA vasculitis nephritis;
Risk factor;
Predictive model
- From:
International Journal of Pediatrics
2025;52(8):536-540
- CountryChina
- Language:Chinese
-
Abstract:
IgA vasculitis nephritis（IgAVN）is a common cause of secondary renal disease in children. Recent studies have identified several risk factors associated with the onset and prognosis of IgAVN，including older age，persistent purpura，severe gastrointestinal manifestations，and elevated levels of galactose-deficient IgA1. Based on these factors，developing predictive models for the risk and prognosis of IgAVN and formulating individualized treatment plans are essential for improving the overall therapeutic efficacy and prognosis of IgAVN.With the growing availability of medical big data，increasing attention has been directed toward the development of predictive models based on clinical variables，including general characteristics，clinical manifestations，and laboratory parameters. This review summarizes the current evidence on risk factors and predictive models for the development and prognosis of IgAVN in pediatric populations.
