The role and mechanism of mucosal immunity in respiratory viral infections
10.3760/cma.j.issn.1673-4408.2025.08.002
- VernacularTitle:黏膜免疫在呼吸道病毒感染中的作用及机制
- Author:
Hao ZHENG
1
;
Gen LU
;
Li HUANG
Author Information
1. 广州医科大学附属妇女儿童医疗中心急诊科 510623
- Keywords:
Mucosal immunity;
Respiratory viral infection;
Children
- From:
International Journal of Pediatrics
2025;52(8):509-514
- CountryChina
- Language:Chinese
-
Abstract:
Respiratory tract infections are common types of infectious diseases in children，involving a variety of immune responses. Understanding the immune mechanisms between viruses and hosts during respiratory infections helps to improve the prevention and treatment of viral infections. The mucosal immune system，as the first line of defense for the body，protects the respiratory tract from pathogen invasion through physical barriers，chemical barriers，microbial barriers，immune cells，and lymphatic tissue. In addition，mucosal immunity also contributes to tissue repair after infection. This article briefly reviews the composition of mucosal immunity and its immune mechanisms in respiratory viral infections，providing a reference for the research of anti-respiratory viral infections and mucosal vaccines.
