Progress on the mechanism of ferritin in respiratory tract infection
10.3760/cma.j.issn.1673-4408.2025.06.007
- VernacularTitle:铁蛋白与呼吸道感染相关机制研究进展
- Author:
Shun ZHU
1
;
Gen LU
Author Information
1. 广州医科大学附属妇女儿童医疗中心呼吸科 510623
- Keywords:
Ferritin;
Respiratory tract infection;
Iron metabolism;
Mechanism;
Immunity
- From:
International Journal of Pediatrics
2025;52(6):390-394
- CountryChina
- Language:Chinese
-
Abstract:
Respiratory tract infection is the most common infectious disease in children and has an impact on children's health worldwide.As a key iron storage protein，ferritin not only participates in maintaining the balance of iron metabolism in the body，but also plays an important role in the pathogenesis of various respiratory infections.In the infected state，ferritin can block pathogens' acquisition of iron，reduce excess iron damage to organelles，maintain blood sugar homeostasis，and affect inflammatory response and immune function.Therefore，when infection occurs，the body's ferritin level affects the prognosis of the disease.This article aims to explore the mechanism of ferritin in respiratory tract infections and provide new directions for future treatment strategies.
