Progress on azithromycin in the treatment of non-cystic fibrosis bronchiectasis in children
10.3760/cma.j.issn.1673-4408.2025.06.006
- VernacularTitle:阿奇霉素治疗儿童非囊性纤维化支气管扩张症的研究进展
- Author:
Jincui HAN
1
;
Donghong PENG
Author Information
1. 重庆医科大学附属儿童医院呼吸科 国家儿童健康与疾病临床医学研究中心 儿童发育疾病研究教育部重点实验室 儿童代谢与炎症性疾病重庆市重点实验室 400014
- Keywords:
Children;
Azithromycin;
Non-cystic fibrosis bronchiectasis
- From:
International Journal of Pediatrics
2025;52(6):385-389
- CountryChina
- Language:Chinese
-
Abstract:
In developing countries，non-cystic fibrosis bronchiectasis is more common compared to cystic fibrosis bronchiectasis. Bronchiectasis seriously affects the quality of survival and growth of children，and there is no specific treatment.Azithromycin has anti-inflammatory and broad immunomodulatory effects in addition to antibacterial effects. A number of clinical studies have shown the effectiveness of azithromycin in the treatment of children with non-cystic fibrosis bronchiectasis，but the drug resistance caused by the application of azithromycin and azithromycin-related adverse reactions during the treatment have also attracted attention.This article reviews the application of azithromycin in children with non-cystic fibrosis bronchiectasis.
