Advance in early biomarkers of renal tubular injury
10.3760/cma.j.issn.1673-4408.2025.06.004
- VernacularTitle:肾小管损伤早期生物标志物研究进展
- Author:
Yanlin WU
1
;
Li SHEN
;
Yulin KANG
Author Information
1. 上海市儿童医院 上海交通大学医学院附属儿童医院肾脏风湿科 200062
- Keywords:
Acute kidney injury;
Renal tubule;
Biomarker;
Early diagnosis
- From:
International Journal of Pediatrics
2025;52(6):376-380
- CountryChina
- Language:Chinese
-
Abstract:
The early biomarkers of renal tubular injury is critical for the early diagnosis and management of acute kidney injury（AKI）. Understanding these biomarkers facilitates the early diagnosis，treatment and prognostic evaluation of AKI. This article reviews the current status of clinical application of AKI biomarkers，and the progress of early biomarkers of renal tubular injury.The discovery and validation of novel biomarkers and their application in clinical practice are summarized as well. Furthermore，it demonstrates the localization of these biomarkers in renal tubule，as well as their significance and challenges in the personalized management of AKI.
