Four nutritional screening tools for evaluating the nutritional status of children with aplastic anemia
10.3760/cma.j.issn.1673-4408.2025.05.014
- VernacularTitle:四种营养筛查工具对再生障碍性贫血儿童的营养评估
- Author:
Memet GULIBAHAR
1
;
Yu LIU
;
Chuncan WU
;
Changda ZHAO
;
Yingbin YUE
;
Mei YAN
Author Information
1. 新疆医科大学第一附属医院儿内一科，乌鲁木齐 830054
- Keywords:
Children;
Aplastic anemia;
Body mass index;
Nutritional assessment;
Combined index
- From:
International Journal of Pediatrics
2025;52(5):353-358
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the nutritional status of children with aplastic anemia（AA）using the children's nutritional risk index（CNRI），prognostic nutritional index（PNI），controlling nutritional status（CONUT），instant nutritional assessment（INA），and combined index（CI），in order to provide scientific evidence to support clinical diagnosis and treatment.Methods:A retrospective analysis was conducted on the clinical data of pediatric AA patients treated in the Department of Pediatrics，Ward 1，First Affiliated Hospital of Xinjiang Medical University from January 1st，2019 to April 30st，2024.Nutritional status was assessed using CNRI，PNI，CONUT，and INA，and integrated into CI.The agreement between different nutritional screening tools was evaluated using Kappa statistics. Results:A total of 68 pediatric AA patients were included，with an overall malnutrition prevalence of 44.1%.The malnutrition rates were 39.4% in the body mass index（BMI）normal group and 48.6% in the BMI abnormal group.Across disease severity groups，malnutrition was observed in 66.67% of very severe AA（VSAA）patients，54.17% of severe AA（SAA）patients，and 28.13% of non-severe AA（NSAA）patients，and the difference was statistically significant（ χ2=6.778， P=0.034）. Kappa analysis demonstrated the highest concordance between CONUT，INA，and CI，with Kappa values of 0.882（ P<0.001）. Conclusion:Pediatric AA patients have a high prevalence of malnutrition，and their nutritional status decline significantly with increasing disease severity.CONUT and INA are effective tools for assessing nutritional status in children with AA，providing reliable evidence for clinical evaluation.
