Advance in drug therapy for acute kidney injury
10.3760/cma.j.issn.1673-4408.2025.05.006
- VernacularTitle:急性肾损伤的药物治疗进展
- Author:
Xiaohe CHEN
1
;
Mengyuan WU
;
Wenyong XIA
;
Xuhua GE
Author Information
1. 南京医科大学附属儿童医院重症医学科 210019
- Keywords:
Acute kidney injury;
Drug therapy;
Targeted drugs;
Nanomedicines;
Antioxidants
- From:
International Journal of Pediatrics
2025;52(5):315-320
- CountryChina
- Language:Chinese
-
Abstract:
Acute kidney injury（AKI）is a clinical syndrome characterized by a rapid decline in renal function. Treatment strategies for AKI primarily focus on treating the underlying disease，providing supportive care，and preventing complications. However，the prognosis remains poor due to the lack of targeted drug therapies.In recent years，with a deeper understanding of the pathophysiological mechanisms of AKI，numerous new drugs and therapeutic methods have emerged and are currently under evaluation. This review aims to thoroughly analyze the latest advancements in AKI drug therapy，covering the development of targeted drugs，innovative applications of nanomedicines，and new breakthroughs and expansions in the use of traditional drugs in the treatment of AKI，in order to provide new ideas and strategies for clinical treatment.
