Progress on gut microbiota in early life and neurodevelopment of premature infants
10.3760/cma.j.issn.1673-4408.2025.02.005
- VernacularTitle:生命早期肠道菌群与早产儿神经发育的研究进展
- Author:
Yuqian WANG
1
;
Xuwu XIAO
Author Information
1. 大连医科大学附属第二医院新生儿科 116000
- Keywords:
Gut microbiota;
Microbiota-gut-brain axis;
Neurodevelopment;
Early life;
Premature infants
- From:
International Journal of Pediatrics
2025;52(2):93-97
- CountryChina
- Language:Chinese
-
Abstract:
The gut microbiota is of great significance for children's health.An increasing number of studies indicate that gut microbiota is one of the potential mediators affecting human neurodevelopment and neuropsychiatric dysbiosis.In early life，there is a significant overlap between the development window of gut microbiota and the nervous system.Premature infants are at high risk of developing gut microbiota dysbiosis and neurodevelopmental disorders.However，the connection between gut microbiota in early human life and neural development remains unclear.This article reviews the relationship between gut microbiota in early life and neurodevelopment in premature infants，with the aim of contributing to identify predictive biomarkers and potential therapeutic targets for healthy neurological development in premature infants.
